Charles River Laboratories International, Inc. research snapshot

CRL AI Stock Analysis

CRL AI stock analysis currently reads Charles River Laboratories as a specialized life sciences services company with strong customer relevance in drug discovery, preclinical safety testing, research models, and biologics quality support. The business has real client switching costs and scientific know-how, but FY2025 GAAP earnings were hit by impairments, DSA demand stayed soft, and the stock has already rebounded sharply into July 2026. The CRL AI stock forecast is scenario-based, not a precise price prediction, and the current setup needs evidence that bookings, revenue, margins, and free cash flow can keep recovering.

Current price

$228.68

Market cap

$11.02 billion verified market cap

AI score

61 / 100

Rating

High-quality life sciences services franchise, but valuation now expects a demand recovery

Trend status

Strong short-term rebound above the 50-day and 200-day averages, with RSI readings ranging from positive to overbought by provider

Data cutoff (updated weekly)

July 8, 2026

Informational use only. This page is not investment advice.

Research quality check

information Richness
A-level information richness. CRL has long public-company history, SEC filings, investor releases, segment disclosures, quote data, third-party financial databases, and current technical indicator coverage.
bias Check
The main AI bias risk is over-weighting the defensive life sciences outsourcing narrative while under-weighting impaired assets, weak GAAP profit, customer funding cycles, non-human primate supply risk, regulatory scrutiny, divestitures, leverage, and the possibility that the 2026 recovery is already priced in.
ai Confidence
High for FY2025 revenue, FY2025 GAAP loss, Q1 2026 revenue, share count, cash, debt, free cash flow, market-cap math, and valuation ratios because company releases and third-party financial sources align closely. Medium for forward ranges because biotech funding, DSA bookings, divestitures, large model supply, and valuation multiples can change quickly.
investment Certainty
Medium. CRL has a hard-to-replace research services position, but investment certainty is lower than data confidence because GAAP earnings remain distorted, organic growth is muted, and the stock price already reflects a recovery from the 2025 downturn.

Quick verdict table

DimensionConclusionConfidence
Business qualityCRL sells essential research models, discovery, safety assessment, microbial testing, biologics testing, and related services to pharma, biotech, government, and academic customers.High
MoatScientific expertise, regulated facilities, validated study processes, client relationships, global scale, and hard-to-replicate model supply create meaningful switching costs.Medium-high
ManagementCEO Birgit Girshick is leading the 2026 recovery and portfolio reshaping phase, while recent impairments and divestitures keep capital allocation under review.Medium
Financial trendFY2025 revenue fell 0.9% to $4.015 billion and GAAP common net loss was $144.3 million, while Q1 2026 revenue rose 1.2% to $995.8 million with a GAAP loss per share of $0.30.High
ValuationAt $228.68, CRL trades near 20.9x company 2026 non-GAAP EPS midpoint, 3.75x book value, and 28.2x TTM free cash flow per share.Medium-high
Technical trendThe stock is above the 50-day and 200-day moving averages after a sharp rally, with resistance near the July 2026 high and risk if price loses the breakout area.Medium
Risk levelKey risks are DSA demand weakness, biotech funding pressure, study cancellations, animal supply and regulatory risk, integration and impairment risk, divestiture execution, leverage, and high expectations after the rally.Medium-high
AI confidenceDescriptive confidence is high because the reported data is well sourced. Return confidence is lower because bookings, customer budgets, interest rates, and sentiment drive the next move.High data confidence
Investment certaintyCRL looks like a durable franchise, but the current price leaves less room for disappointment unless 2026 revenue and margin recovery improves from here.Medium

CRL AI stock forecast

CRL AI Stock Forecast Scenarios

The CRL AI stock forecast uses scenario math around the $228.68 price reference, management 2026 non-GAAP EPS midpoint near $10.95, and a three-year earnings multiple framework. The audited model produced a bearish area near $116.30, a base area near $221.70, and a bullish area near $312.00 before any dividends.

Bullish case

$295 to $320

More likely if DSA bookings convert to revenue, pharma and biotech funding improves, restructuring savings lift margins, Manufacturing demand stabilizes, adjusted EPS compounds near high single digits, and investors keep valuing CRL above 20x earnings.

Base case

$210 to $230

More likely if reported revenue is flat to slightly higher, organic growth turns positive later in 2026, impairments fade from investor focus, and the market values CRL near a high-teens earnings multiple.

Bearish case

$105 to $125

More likely if DSA demand weakens again, cancellations rise, divestitures reduce scale, free cash flow falls, leverage concerns return, or the stock re-rates toward a low-teens earnings multiple.

CRL AI technical analysis

CRL AI Technical Analysis

CRL AI technical analysis is constructive but extended as of the July 8, 2026 cutoff. StockAnalysis showed a $228.68 close on July 7, 2026, with the 50-day and 200-day moving averages near $180 and RSI at 78.88, while Investing.com showed daily indicators in a strong buy posture with RSI near 60.9. Provider differences make the level map more useful than a single signal.

LevelValueWhy it matters
Current price$228.68StockAnalysis reported this July 7, 2026 close, used as the quote reference for market-cap and valuation math.
Immediate support$223 to $229This area covers the July 6 intraday low near $223.85 and the July 7 close, so losing it would show weak follow-through after the rebound.
Deeper support$214 to $216Recent trading references around late June 2026 placed CRL near the mid-$210s before the July push, making this a practical pullback zone to monitor.
Major trend supportAbout $180StockAnalysis listed both the 50-day and 200-day moving averages near $180, far below the current price after the rally.
Near resistance$231 to $233CRL closed at $231.43 on July 6, 2026 and reached a same-day high near $232.32 in company IR historical price data.
Moving averages50-day about $180.40 and 200-day about $180.44The price is well above both references, which supports the trend but also increases pullback risk if buyers fade.
MomentumRSI range about 61 to 79Investing.com showed RSI near 60.9, while StockAnalysis showed 78.88, so momentum is positive but may be stretched depending on data provider timing.
Volume20-day average volume about 856,599 sharesStockAnalysis reported this average volume reference, useful for judging whether breakouts above the July high have enough participation.
VolatilityHigh relative to the market with beta near 1.40StockAnalysis listed beta near 1.40, so position sizing should allow for larger swings than a broad-market index.
InvalidationClose below $214A close below the recent breakout base would weaken the rebound setup and shift focus back to the 50-day and 200-day averages.

CRL AI trading strategy

CRL AI Trading Strategy Framework

The CRL AI trading strategy below is a rules-based research framework, not personal advice. It combines booking recovery checks, margin evidence, leverage monitoring, valuation discipline, and technical invalidation levels.

Trend-following setup

Watch for CRL to hold above the $231 to $233 resistance area while Q2 results confirm DSA bookings, stable RMS demand, Manufacturing margin support, and free cash flow conversion.

A failed breakout back below $223 or a close below $214 should reduce setup confidence because it would show the July rally could not hold.

Mean-reversion setup

If CRL pulls back toward $214 to $223 without a deterioration in bookings, compare the valuation reset with non-GAAP EPS guidance, free cash flow per share, debt, and customer demand commentary.

Do not treat a pullback as benign if organic revenue misses guidance, DSA cancellations rise, or free cash flow weakens faster than revenue.

Fundamental monitor

Track DSA net bookings, RMS large model trends, Manufacturing divestiture impact, non-GAAP operating margin, free cash flow, total debt, repurchases, and the next earnings date around August 5, 2026.

Position sizing should reflect that CRL is a leveraged life sciences services business exposed to biotech funding, pharma budget cycles, and regulatory risk.

Investment research summary

Four-master Research Compression

Business essence

Customers pay CRL because drug discovery and preclinical development are expensive, regulated, and time-sensitive. CRL helps clients source models, run studies, assess safety, and support quality testing so therapies can move through development more efficiently.

Moat

The moat is strongest in scientific expertise, global facilities, regulated process history, validated study data, client trust, and scale. It is weaker than a patent monopoly because customers can insource some work or use rival contract research organizations.

Munger risk inversion

The thesis fails if biotech funding stays weak, DSA bookings do not convert, large model supply becomes constrained or controversial, impairments point to deeper business issues, or customers reduce outsourced research spending.

Management

Management has built CRL into a broad life sciences services platform and continues to pursue efficiency, acquisitions, divestitures, and buybacks. CEO Birgit Girshick now has to prove that portfolio reshaping improves returns after recent impairment charges.

Industry trend

CRL sits inside a long-term trend toward outsourced drug discovery, biologics quality testing, and more complex therapeutic development. The offset is that biotech funding and pharma pipeline priorities can pause demand for several quarters.

Valuation and margin of safety

At about 21x management 2026 non-GAAP EPS midpoint and 28x TTM free cash flow per share, CRL is not priced as distressed. Margin of safety depends on DSA recovery, fewer one-time charges, stable free cash flow, and disciplined capital allocation.

Source-backed data

CRL Data Table

Every metric below includes a source and last verification date.

MetricValueSourceLast verified
CRL quote reference$228.68 close on July 7, 2026StockAnalysis CRL market cap pageJuly 8, 2026
Market capitalization verification$11.02 billion calculated from $228.68 x 48.17 million sharesPineify financial_rigor.py and StockAnalysis share dataJuly 8, 2026
Shares outstanding48.17 million shares outstandingCRL Q1 2026 balance sheet and StockAnalysis statisticsJuly 8, 2026
FY2025 revenue and GAAP common net loss$4.015 billion revenue and $144.3 million GAAP net loss available to common shareholdersCRL FY2025 earnings release and StockAnalysis financialsJuly 8, 2026
FY2025 segment revenueRMS $846.1 million, DSA $2.40 billion, Manufacturing $766.4 millionCRL FY2025 earnings releaseJuly 8, 2026
Q1 2026 revenue and EPS$995.8 million revenue, GAAP EPS loss of $0.30, and non-GAAP EPS of $2.06CRL Q1 2026 earnings releaseJuly 8, 2026
Cash and debt$191.83 million cash and equivalents and about $3.06 billion total debt at March 28, 2026CRL Q1 2026 balance sheet and StockAnalysis balance sheetJuly 8, 2026
Free cash flow$391.29 million TTM free cash flow and $8.12 free cash flow per shareStockAnalysis CRL cash flow statementJuly 8, 2026
Valuation ratios20.88x non-GAAP EPS midpoint, 3.75x book value, 28.16x free cash flow, and 0.00% dividend yieldPineify financial_rigor.py and StockAnalysis statisticsJuly 8, 2026
Company business descriptionProvider of products and services that help pharmaceutical, biotechnology, government, and academic clients accelerate research and drug developmentCRL Investor Relations FY2025 releaseJuly 8, 2026
Technical trend dataPrice above 50-day and 200-day moving averages near $180, RSI readings positive to overbought, and near resistance around $231 to $233StockAnalysis, Investing.com, and CRL historical price lookupJuly 8, 2026

Frequently Asked Questions

This CRL AI stock analysis is for informational and educational use only. It is not investment advice, a recommendation, or a guarantee of future returns. Forecast ranges are scenario estimates based on available public data as of July 8, 2026, and they can be wrong if fundamentals, market prices, biotech funding, bookings, regulatory conditions, debt costs, or investor sentiment change.