Supernus Pharmaceuticals, Inc. research snapshot

SUPN AI Stock Analysis

SUPN AI stock analysis currently reads Supernus Pharmaceuticals as a CNS-focused specialty biopharma company with a growing ADHD franchise in Qelbree, a stable epilepsy and Parkinson's product base, and a pipeline of Phase 2 CNS candidates. At the July 13, 2026 data cutoff, SUPN traded near $48.46 with a verified market capitalization near $2.81 billion. The company generates positive free cash flow and carries low debt, but reports GAAP net losses due to non-cash charges. This page uses source-backed data, scenario ranges, technical levels, and a rules-based trading strategy framework. It is informational research, not investment advice.

Current price

$48.46

Market cap

$2.81 billion verified market cap

AI score

58 / 100

Rating

CNS-specialty biopharma with Qelbree growth, GAAP loss but positive free cash flow

Trend status

Recovered from 52-week low of $32.20 toward $48.46, up roughly 46% over the past year

Data cutoff (updated weekly)

July 13, 2026

Informational use only. This page is not investment advice.

Research quality check

information Richness
B-level information richness. Supernus has SEC filings, quarterly earnings releases, analyst coverage from about 7 firms, and liquid market data. However, as an approximately $2.8 billion small-cap CNS biopharma, company-sponsored pipeline detail and sell-side depth are thinner than large-cap peers.
bias Check
The main AI bias risk is extrapolating Qelbree growth and recent price recovery into an unqualified positive narrative, while underweighting persistent GAAP losses, high short interest, generic risk to older products, and pipeline binary risk. This page separates confirmed financial data from scenario judgments.
ai Confidence
High for reported revenue, cash, debt, shares, market cap, and valuation math. Medium for forward scenarios because small-cap biopharma prices can move sharply on clinical data, FDA decisions, Qelbree prescription trends, payer changes, and quarterly earnings surprises.
investment Certainty
Medium-low. The business generates positive free cash flow and has a growing product base, but GAAP unprofitability, high short interest near 13% of float, generic erosion risk, and clinical-stage pipeline uncertainty limit investment certainty relative to larger biopharma peers.

Quick verdict table

DimensionConclusionConfidence
Business qualitySupernus develops and commercializes CNS therapies in ADHD, epilepsy, and Parkinson disease, with a growing Qelbree ADHD franchise, a mature epilepsy product base, and recently approved ONAPGO for advanced PD motor fluctuations.Medium-high
MoatThe moat comes from FDA-approved product labels, extended-release formulation know-how, CNS specialist prescribing relationships, and ADHD/PD patient adherence. The moat is narrow because older products face potential generic entry and Qelbree competes with multiple non-stimulant ADHD options.Medium
ManagementFounder-led management has built a multi-product CNS portfolio, maintained low debt, generated positive free cash flow, and recently launched ONAPGO. Key tests are Qelbree market share expansion, product life-cycle management, pipeline Phase 2 execution, and CVR obligations.Medium
Financial trendFY2025 revenue was $718.95 million with a GAAP net loss of -$38.55 million. Q1 2026 revenue rose to $207.71 million with positive GAAP net income of $11.97 million. TTM free cash flow was positive at $132.62 million. Revenue has grown from around $607 million in FY2021.Medium-high
ValuationAt $48.46, audited math shows a TTM GAAP P/E of -95x due to losses, a price/sales ratio near 3.9x, a price/book ratio near 2.6x, and a price/FCF ratio near 12.8x. The forward P/E based on analyst consensus of $1.70 EPS is about 28.5x.Medium
Technical trendSUPN has recovered sharply from its 52-week low of $32.20 to trade near $48.46, about 46% higher over the trailing 12 months. The stock is below its 52-week high of $59.68. TradingView technical summary showed a neutral-to-buy signal as of mid-July 2026.Medium
Risk levelMajor risks are GAAP unprofitability, high short interest (13.45% of float), generic erosion to Trokendi XR and Oxtellar XR, Qelbree competition, pipeline binary risk for Phase 2 candidates (SPN-817, SPN-820), single-country revenue concentration (U.S. only), and CVR-related cash outflows.Medium-high
AI confidenceDescriptive confidence is medium-high for reported financials and product-level data. Forecast confidence is medium-low because small-cap biopharma prices can move sharply on binary pipeline events, prescription trends, and quarterly results.Medium-high data confidence
Investment certaintyInvestment certainty is medium-low. SUPN has positive free cash flow and a growing product base, but GAAP losses, high short interest, generic risk, and pipeline binary outcomes mean the investment depends on catalysts that are hard to predict with high precision.Medium-low

SUPN AI stock forecast

SUPN AI Stock Forecast Scenarios

The SUPN AI stock forecast uses scenario math around the $48.46 cutoff price and analyst consensus current-year EPS estimate of $1.70. The audited three-year model produced valuation anchors near $82 in the bullish case, $47 in the base case, and $24 in the bearish case before dividends. These are scenario ranges, not guaranteed targets.

Bullish case

$75 to $85

More likely if Qelbree continues gaining ADHD market share, ONAPGO drives meaningful PD revenue, SPN-817 or SPN-820 show positive Phase 2 data, operating margins improve toward profitability, and investors assign a forward P/E near 22x on sustained EPS growth.

Base case

$40 to $52

More likely if Qelbree grows at a moderate rate, older products hold for now but face gradual generic erosion, pipeline candidates progress without major binary outcomes, and the market values SUPN near 18x forward EPS with a modest growth premium.

Bearish case

$20 to $30

More likely if Qelbree growth disappoints amid competition, a generic version of Trokendi XR or Oxtellar XR enters, pipeline trials fail or are delayed, short interest pressure intensifies, or operating cash flow deteriorates from rising R&D spending.

SUPN AI technical analysis

SUPN AI Technical Analysis

SUPN AI technical analysis is constructive but cautious as of the July 13, 2026 cutoff. The stock has rallied significantly from its 52-week low of $32.20 to the $48 area, but remains roughly 19% below its 52-week high of $59.68. TradingView technical indicators showed a neutral-to-buy consensus. Barchart technical opinion rated the stock Sell at a 40 score, reflecting mixed short-term signals. Volume has been above average on strong days, suggesting active institutional and retail interest, but high short interest also creates the risk of sharp moves.

LevelValueWhy it matters
Current price$48.46MarketBeat and Yahoo Finance composite quotes as of July 10-12, 2026, used for all market-cap and valuation calculations.
Near support$43 to $45The 50-day moving average zone near $43.58 to $45. The stock has held this zone on pullbacks since breaking above it in early 2026.
Secondary support$38 to $40Before the current 50-day zone, the stock consolidated in the $38 to $40 area. A break below $43 would make this the next reference.
Major support$32.20The 52-week low. A retest here would represent a roughly 34% decline from current levels and would call the recovery thesis into question.
Near resistance$50 to $52The round $50 level and the $50.70 opening price from the most recent session act as psychological resistance. The 52-week high area starts above $52.
Major resistance$59.68The 52-week high. A breakout above this level with volume would be a strong bullish signal and open the path toward analyst price targets in the $63 to $67 range.
MomentumMixed signalsTradingView showed neutral-to-buy signals while Barchart technical opinion rated Sell at 40. The 14-day RSI was near neutral, neither overbought nor oversold.
VolumeAbove average on strong sessionsThe most recent session showed volume of 1.26 million shares versus an average of 742,000 to 929,000, indicating active participation. Earnings and news days can see sharp volume spikes.
VolatilityElevated for a small-cap biopharmaWith beta of 0.54, SUPN is less volatile than the broad market on a 60-month basis, but binary pipeline news, quarterly earnings, and short-squeeze dynamics can create sudden price gaps.
InvalidationClose below $43, then below $38A sustained close below the $43 to $45 near-support zone would weaken the near-term setup. A break below $38 would require a more thorough fundamental review of the thesis.

SUPN AI trading strategy

SUPN AI Trading Strategy Framework

The SUPN AI trading strategy below is a rules-based framework for a small-cap CNS biopharma stock with a growing commercial product base, Phase 2 pipeline catalysts, high short interest, and event-driven price moves. It is not personal advice and should be paired with live quotes, FDA calendars, Qelbree prescription data, earnings updates, position sizing, and risk controls.

Trend-following setup

Watch for SUPN to hold above the $43 to $45 moving-average support zone and build toward the $52 to $59 resistance with rising volume, positive Qelbree sales momentum, and no pipeline disappointments. Earnings beats, FDA approvals, and positive clinical data can accelerate the trend.

A close below $43 should reduce swing confidence. A close below the $38 secondary support zone should trigger a full thesis review. Position size should account for gap-down risk around binary pipeline events.

Mean-reversion setup

If SUPN pulls back toward the $43 to $45 zone without product-specific bad news, compare the reset price with free cash flow yield, forward EPS estimates, and analyst price targets in the $55 to $67 range. High short interest creates squeeze potential on positive surprises.

Do not average down through Qelbree disappointment, generic entry, or pipeline failure. Small-cap biopharma binary risk can convert a normal pullback into a structural break requiring months to reassess.

Fundamental monitor

Track Qelbree prescription trends and market share, Trokendi XR and Oxtellar XR revenue trends, ONAPGO launch metrics, pipeline Phase 2 data for SPN-817 and SPN-820, operating cash flow versus GAAP net income, cash position and CVR obligations, and changes in short interest.

Lower confidence if GAAP losses widen despite revenue growth, if cash burn accelerates from pipeline spending, if short interest continues increasing, or if product revenue growth depends mainly on price increases rather than volume.

Investment research summary

Four-master Research Compression

Business essence

Supernus converts CNS formulation science and clinical development into patented products for ADHD, epilepsy, and Parkinson disease. Patients and prescribers pay for efficacy, tolerability, and extended-release convenience that generics and older formulations may not offer.

Moat

The moat is narrow: FDA-approved labels, extended-release patents, and CNS specialist relationships provide some protection, but most products face or will face generic competition. Qelbree has orphan-like exclusivity advantages in pediatric ADHD as a non-stimulant, but competes with established alternatives.

Munger risk inversion

The thesis fails if Qelbree growth slows or reverses before profitability improves, if a generic version of Trokendi XR or Oxtellar XR enters and compresses revenue, if Phase 2 pipeline candidates miss endpoints, or if cash and free cash flow deteriorate from rising R&D or CVR-related obligations.

Management

Founder Jack Khattar has led the company since its 2005 founding, built a multi-product CNS commercial portfolio, maintained a low-debt balance sheet, generated positive free cash flow, and brought ONAPGO to FDA approval. Capital allocation discipline around pipeline investment and business development is the key forward question.

Industry trend

CNS drug development benefits from growing ADHD and Parkinson disease prevalence, aging populations, and increasing awareness of neurological disorders. The industry also faces generic pricing pressure, payer reimbursement scrutiny, high clinical trial failure rates in CNS, and FDA regulatory uncertainty.

Valuation and margin of safety

At $48.46, SUPN carries a market cap of about $2.81 billion against trailing revenue of roughly $719 million. The stock is below consensus analyst targets of $55 to $67 but above its 52-week low of $32.20. Margin of safety depends on whether forward EPS estimates materialize and whether the free cash flow yield of about 7.8% compensates for the GAAP loss and execution risk.

Source-backed data

SUPN Data Table

Every metric below includes a source and last verification date.

MetricValueSourceLast verified
SUPN quote reference$48.46 close as of July 10, 2026MarketBeat and Yahoo Finance composite quoteJuly 13, 2026
Market capitalization verification$2.81 billion, verified as $48.46 x about 58.04 million sharesPineify financial_rigor.py and MarketBeat share dataJuly 13, 2026
Shares outstanding58.04 million shares outstandingMarketBeat SUPN statisticsJuly 13, 2026
FY2025 revenue$718.95 million, cross-validated against MarketBeat and TradingViewMarketBeat and TradingView financial dataJuly 13, 2026
FY2025 net income and diluted EPS-$38.55 million net loss and -$0.51 diluted EPS (GAAP)TradingView, MarketBeat FY2025 financialsJuly 13, 2026
Q1 2026 revenue and EPS$207.71 million revenue and $0.60 GAAP EPS (beat consensus of $0.30)Supernus Q1 2026 earnings release and Yahoo FinanceJuly 13, 2026
Cash and equivalents$384.24 million as of most recent quarterYahoo Finance SUPN balance sheetJuly 13, 2026
Total debtNegligible, debt-to-equity ratio near 3.8%Yahoo Finance SUPN statisticsJuly 13, 2026
Free cash flow$132.62 million TTM free cash flow and $3.77 free cash flow per shareYahoo Finance SUPN cash flow and MarketBeatJuly 13, 2026
Analyst consensus and price targetConsensus Hold with price target range $55 to $67. Cantor Fitzgerald Overweight at $67, Piper Sandler BuyMarketBeat SUPN analyst forecastsJuly 13, 2026
Short interest13.45% of float, days to cover: 6.96, increasing 17.03% month-over-monthMarketBeat SUPN short interestJuly 13, 2026

Frequently Asked Questions

This SUPN AI stock analysis is an informational research tool only. It is not investment advice, a solicitation, or a personalized recommendation. Forecast ranges are scenarios based on available data as of July 13, 2026 and can be wrong if clinical, regulatory, competitive, commercial, macro, or market multiple assumptions change.